1. general treatment: high blood pressure and the incidence of central nervous system dysfunction, should not do any work
2. step-down drug treatment
(A) of the angiotensin-converting enzyme inhibitors: the current application of captopril, enalapril.
(B) calcium antagonists: a set of different chemical structure, mechanism of action are not the same drug, as the inhibition of calcium through the cell membrane calcium channels in the stream, which is called calcium channel antagonistic.
Anti-agent: commonly used drugs verapamil, diltiazem and nifedipine-Zhuo, nitrendipine.
(C) vasodilator: a direct relaxation of vascular smooth muscle, blood vessels and lower blood pressure, drugs commonly used: 1. Sodium, 2. Pressure will be a long, 3. Hydralazine.
(D) in the role of the sympathetic nervous system, blood pressure drugs:
4.1 central sympathetic inhibitor: (1), clonidine, (2) methyldopa.
4.2. Ganglion blocker: Alfonso have used it special for the treatment of hypertensive encephalopathy.
4.3. Postganglionic sympathetic nerve blockers: in the peripheral sympathetic norepinephrine depletion of storage, and the blood pressure up. Commonly used drugs are: (1) guanidine bromide, (2) reserpine.
4.4. Adrenergic receptor blocker:
(1) β-blocker; labetalol is recommended by the WHO blood pressure drug, D-vinegar peace of mind.
(2) α-blocker: those who have used prazosin, and doxazosin.
(E) diuretic blood pressure drug:
1. Thiazides: is the most widely used oral diuretic blood pressure medicine, Hydrochlorothiazide.
2. Chlorthalidone
3. Furosemide,
4. Dapsone HD-PI,
3. drug treatment
(A) individual: Depending on the patient’s physiological and pathological features of disease progression and complications, and use different drugs in different doses.
(B) combination,
(C) the treatment of classification: the general high blood pressure, using less side-effects of drugs, failure to achieve a satisfactory effect can be used to gradually increase one or more of the different mechanism of action of the drug could be considered the treatment of classification.
(D)
I: diuretics, β-blockers, calcium antagonists, angiotensin-converting enzyme inhibitor may make use of a drug, a void would be able to another.
II: combination, and two drugs, began at a young age, the effective date, null and void if transferred to three.
III: The combination of the three drugs used.
IIII. three poor treatment, can be used for guanidine bromide or clonidine.
